Julian Gomez-Cambronero, Ph.D., professor of biochemistry and molecular biology at the Wright State University Boonshoft School of Medicine, has been named the Brage Golding Distinguished Professor of Research.
Named after Wright State’s first president, the award recognizes outstanding research by a Wright State faculty member. The title Distinguished Professor of Research is a special rank awarded by the Board of Trustees to a faculty member who has produced a significant body of work in scholarship, research or the creative arts, which brings distinction to the university and national or international recognition to the faculty member.
Cambronero and his research team have discovered a key protein that plays a critical role in the development of breast cancer tumors and the spread of the disease to the nearby lungs.
His findings, which were published in the July 2013 leading cancer journal Oncogene, attribute the cancer’s growth to a protein called Phospholipase D (PLD). Cambronero and his team found that by introducing two new chemical inhibitors of PLD, they could shrink tumor growth and reduce subsequent metastasis by around 70 percent.
“Although it’s still early to tell, the application of these inhibitors to research in human tissue is the next step that could lead to better, less toxic treatments in the battle against breast cancer,” said Cambronero, who joined Wright State in 1995.
Cambronero has secured more than $6 million in research funding from the National Institutes of Health (NIH), the American Heart Association (AHA), the American Cancer Society and other state and federal sources. He has published more than 90 peer-reviewed publications and presented more than 70 research communications at various conferences and universities nationally and internationally. He also reviews manuscripts for more than 20 scientific journals and grant proposals for the NIH (innate immunity and inflammation) and AHA (cell and molecular signaling).
“Julian has achieved … scholarship accolades while providing extraordinary teaching to medical and graduate students and service within and outside Wright State University,” said Steven J. Berberich, Ph.D., chair of the Department of Biochemistry and Molecular Biology.