Beginning to End

Module Director: Irina Overman, M.D., Internal Medicine and Medical Education

Module Description: The Beginning to End module will focus on the endocrine, gastrointestinal, and reproductive systems under normal and abnormal conditions. The module also advances the concepts of genetics, nutrition, hematology, and human development. Throughout the module, the learner will solve increasingly complex clinical case problems that exemplify core pathophysiologic concepts and make evidence-based decisions about diagnosis and treatment. Presentation and diagnosis of diseases involving all ages will be investigated.

Alignment of WrightCurriculum Educational Objectives & Milestones to the Module Learning Goals

Boonshoft SOM Educational Objectives and Milestones


What competencies / milestones will this unit address? 

Foundational Knowledge – Medical Knowledge: Master fundamental biomedical concepts, terms, processes, and system interactions


Describe normal structure and function of the human body at the molecular, cellular, tissue, organ level and all major organ systems, outlining how anatomy, biochemistry, cell biology and physiology work together


Identify the major diseases and conditions and the ways in which they operate in the body


Use scientific principles underlying diagnostic methodologies

Foundational Knowledge – Medical Knowledge: Describe the determinants of health


Identify and describe the individual and population-level biopsychosocial determinants of health and how these determinants influence populations health status

Foundational Knowledge – Medical Knowledge: Utilize evidence in making clinical decisions


Obtain, analyze, and synthesize information from the medical literature


Define the fundamental statistical tools used in medicine

Application – Patient Care: Diagnose patient health problems


Generate a differential diagnosis by applying knowledge of the basic sciences and pathophysiology

2.2 Define and explain ancillary diagnostics

Application – Patient Care: Propose evidence-based health maintenance and therapeutic options


Propose a treatment plan for common disease processes


Explain the three levels of prevention and the role of health promotion in increasing the health status of patients and populations

Integration – Systems-Based Practice: Connect knowledge of patient populations and health delivery processes in making diagnoses and therapeutic recommendations


Identify and explain population health goals (Foundations)

Integration – Systems-Based Practice: Advocate for the humane, just, safe and prudent care of persons


Identify contextual factors that may affect the health status of an individual patient or population (Foundations)

Human Dimension – Personal and Interpersonal Professional Development Goals: Reflection upon one’s personal strengths and weaknesses to make changes in one’s behavior


Integrate formative feedback from patients, peers, and faculty in order to modify behaviors (Foundations)

Human Dimension – Personal and Interpersonal Professional Development Goals: Communicate and work effectively with others


 Identify roles within teams, and provide/receive effective feedback


Effectively assimilate in various teams, including interprofessional teams


Communicate clearly and empathetically in both written and verbal venues

Human Dimension – Personal and Interpersonal Professional Development Goals: Demonstrate leadership skills in a variety of settings


Identify characteristics of and contribute to the development of a high functioning team

Module-Level Objectives


What are the module-level objectives for this course? 

Boonshoft SOM Objectives


Describe the principles of digestive, reproductive, hematologic, and endocrine physiology and the mechanisms by which their function is maintained in health.

1.1a, 2.2a


Recognize the normal histology and anatomy of the digestive, reproductive, and endocrine systems, and correlate with embryologic development.



Discuss the epidemiology, etiology, pathophysiology, histopathology, and clinical manifestations of diseases of the gastrointestinal, endocrine, reproductive, and hematologic systems.

1.1b, 2.2a


Explain the role of diagnostic modalities in the evaluation of disease related to the gastrointestinal, endocrine, reproductive, and hematologic systems.

1.1c, 2.2a, 2.2b


Justify appropriate pharmacologic and non-pharmacological interventions to treat and prevent disorders of the gastrointestinal, endocrine, reproductive, and hematologic systems.

2.3a, 2.3b, 3.1b, 3.2b


Explain how clinical manifestations of nutritional disorders result from alterations in nutrient acquisition or physiology.

1.1a, 1.1b, 2.2a


Acquire in-depth knowledge of the principles of human genetics and their application to a wide variety of clinical problems.

1.1b, 1.2a, 2.2a, 2.2b


Demonstrate professional behavior during interactions with patients and their families, peers, and instructors in a variety of settings.

4.5a, 4.5b, 4.5c, 5.3a


Use critical judgment and problem-solving skills to integrate the principles of evidence based medicine with biomedical and clinical sciences.

1.3a, 1.3b, 6.2a


Use effective communication and leadership skills when working with others.

4.5a, 4.5b, 4.5c, 4.6a, 4.6c


Perform self-assessment to identify gaps in knowledge and address deficiencies.

4.1a, 6.3a

To review all Boonshoft SOM Educational Milestones please visit the Educational Milestones page.


Last edited on 01/16/2019.